Author

Yujia Cai

Ocean University of ChinaORCID 0000-0002-2955-7289Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yujia Cai1 paper

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Anji Wei· 1 shared Di YiniD· 1 shared Gang CheniD· 1 shared Huangying Le· 1 shared Jianjiang XuiD· 1 shared Jianye ZhangiD· 1 shared Jiaxu HongiD· 1 shared Lijia Tian· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Anji Wei

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintFeb 21, 2023

In Vivo CRISPR Gene Editing in Patients with Herpes Stromal Keratitis

Anji Wei, Di Yin, Zimeng Zhai…·Jiaxu Hong

This study evaluates the safety and efficacy of in vivo CRISPR gene editing targeting HSV-1 in patients with herpes stromal keratitis, finding no detectable off-target effects or adverse events over 18 months.

3 citations

humanCRISPR screen

𝕏 PostBluesky

GeneticsbioRxivPreprintMay 3, 2021

Frameshift and wild-type proteins are highly similar because the genetic code and genomes were optimized for frameshift tolerance

Xiaolong Wang, Quanjiang Dong, Gang Chen…·Yujia Cai

The paper shows frameshift proteins are more similar to wild-type proteins than random, indicating the genetic code and genomes are optimized for frameshift tolerance.

13 citations

statistical model

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