Author

Benedikt Wiestler

TUM KlinikumORCID 0000-0002-2963-7772Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Daniel RueckertiD· 2 shared Jan Stefan KirschkeiD· 2 shared Alessandro CrimiiD· 1 shared Ali ErtürkiD· 1 shared Alice Senta RybaiD· 1 shared Alicia BuckiD· 1 shared Amanda Salviano‐SilvaiD· 1 shared Annika K. WefersiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioinformatics

Daniel RueckertORCID

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4 papers

Recent·Most cited

MedMCP: An Open Agentic Ecosystem for Medical Imaging Workflows

Julian McGinnis, Paul Friedrich, Mark Mühlau, Jan Stefan Kirschke, Martin Andreas Styner, Daniel Rueckert, Philippe Claude Cattin, Benedikt Wiestler

MedMCP provides an agentic framework for medical imaging workflows, enabling non-technical users to apply state-of-the-art image analysis through natural language and shareable workflows.

bioRxiv · Oct 19, 2026 · PreprintBioinformatics

Virtual reality empowered deep learning analysis of brain activity

Doris Kaltenecker, Rami Al-Maskari, Moritz Negwer, Luciano Hoeher, Florian Kofler, Shan Zhao, Mihail Ivilinov Todorov, Zhouyi Rong, Johannes Christian Paetzold, Benedikt Wiestler, Marie Piraud, Daniel Rueckert, Julia Geppert, Pauline Morigny, Maria Rohm, , Ali Ertürk

DELiVR uses VR-generated data to train deep learning models for quantifying c-Fos in cleared mouse brains, revealing new activation patterns in cancer-related brain activity.

Nature Methods · Apr 22, 2024Peer-reviewedBioinformatics

Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability

Richard Drexler, Robin Khatri, Thomas Sauvigny, Malte Mohme, Cécile L. Maire, Alice Senta Ryba, Yahya Zghaibeh, Lasse Dührsen, Amanda Salviano‐Silva, Katrin Lamszus, Manfred Westphal, Jens Gempt, Annika K. Wefers, Julia E. Neumann, Helena Bode, , Franz Lennard Ricklefs

The paper identifies an epigenetic neural signature in glioblastoma that correlates with poor prognosis and therapeutic vulnerability.

bioRxiv · Aug 4, 2023 · PreprintNeuroscience

Pre-operarative Multivariate Connectome Analysis for Glioma Patients

Alessandro Crimi, Benedikt Wiestler, Jan Stefan Kirschke, Sandro Manuel Krieg

This paper constructs speech networks from pre-operative neuroimaging data to identify differences in graph metrics between glioma patients with and without aphasia, aiding surgical decision-making.

bioRxiv · Oct 5, 2018 · PreprintNeuroscience