Author

Lance Y. Xu

Johns Hopkins UniversityORCID 0000-0002-2976-7921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Andrew Jon HollandiD· 1 shared Fang-Chi Chang· 1 shared Zhong Y. YeowiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Andrew Jon HollandORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMay 6, 2026

Centrosome depletion rewires mitosis to impose dependence on the AURK-TPX2 axis

Zhong Y. Yeow, Fang-Chi Chang, Lance Y. Xu, Andrew Jon Holland

The paper identifies genetic suppressors of centrosome depletion sensitivity, revealing the AURKA-TPX2 axis as a critical pathway for spindle assembly under centrosome depletion.

DOI 10.64898/2026.05.02.722379

humangenetic perturbation / CRISPR

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