Author

Zhong Y. Yeow

Johns Hopkins UniversityORCID 0009-0005-0755-3163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Andrew Jon HollandiD· 2 shared Fang-Chi Chang· 1 shared Lance Y. XuiD· 1 shared M. van BreugeliD· 1 shared Sonia SarjuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersCancer Biology

Andrew Jon HollandORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 6, 2026

Centrosome depletion rewires mitosis to impose dependence on the AURK-TPX2 axis

Zhong Y. Yeow, Fang-Chi Chang, Lance Y. Xu, Andrew Jon Holland

The paper identifies genetic suppressors of centrosome depletion sensitivity, revealing the AURKA-TPX2 axis as a critical pathway for spindle assembly under centrosome depletion.

DOI 10.64898/2026.05.02.722379

humangenetic perturbation / CRISPR

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Molecular BiologybioRxivPreprintOct 9, 2024

Mesoscale regulation of MTOCs by the E3 ligase TRIM37

Zhong Y. Yeow, Sonia Sarju, M. van Breugel, Andrew Jon Holland

This paper elucidates how TRIM37 regulates mesoscale MTOCs through a multi-step activation mechanism involving substrate recognition, oligomerization, and dimerization.

2 citations

experimental assay

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