The UPRER governs the cell-specific response of human dopaminergic neurons to mitochondrial stress
Jana Heneine, Claire Sauty-Colace, Christiane Zhu, Benjamin Galet, Justine Guégan, François‐Xavier Lejeune, Thomas Gareau, Noemi Asfogo, Corinne Pardanaud-Glavieux, Olga Corti, Philippe Ravassard, Hélène Cheval
The paper shows that the UPRER coordinates mitochondrial stress responses in human dopaminergic neurons, including mitophagy and lncRNA expression, and identifies a lncRNA involved in translation resumption.
bioRxiv · Jun 17, 2024 · PreprintNeuroscience