Harnessing Diacylglycerol-Terminated Cationic Oligomers for Next-Generation Antibacterial Therapeutics
Qiaomingxuan Liu, Shiwei Zhang, Margaret Pywell, Alysha G. Elliott, Holly E. E. Floyd, Johannes Zuegg, Jessica R. Tait, John F. Quinn, Michael Raymond Whittaker, Muhammad Bilal Hassan Mahboob, Cornelia B. Landersdorfer
This paper synthesizes and evaluates cationic lipid-terminated oligomers (CLOs) with potent and selective antibacterial activity against priority pathogens, showing low toxicity and tunable properties.
European Polymer Journal · Oct 4, 2026Peer-reviewedMicrobiology