Derek Norton

Characterizing the effects of sex, APOE ɛ4, and literacy on mid-life cognitive trajectories: Application of Information-Theoretic model-averaging and multi-model inference techniques to the Wisconsin Registry for Alzheimer’s Prevention Study

The paper uses information-theoretic model-averaging to analyze cognitive decline factors in mid-life, finding sex, literacy, and APOE ɛ4 effects with varying impacts.

Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid

The paper compares cognitive and hippocampal volume decline in asymptomatic adults with and without CSF β-amyloid or tau markers, finding accelerated decline in those with positive markers.

Modifiable risk factors moderate the relationship between amyloid and cognition in midlife

This study shows that hypertension and depression, but not obesity, moderate the link between amyloid and cognitive decline in midlife individuals at risk for Alzheimer's disease.