Cynthia M. Carlsson

This study identifies novel Alzheimer's disease risk loci by analyzing multi-ancestry GWAS data from diverse populations, highlighting the importance of including underrepresented groups in genetic research.

The paper develops an APOE genetic risk score based on neuropathology that better explains CSF biomarker variance than traditional APOE ε4 metrics.

This study identifies blood-based biomarkers associated with Alzheimer's disease genetic risk variants in a large cohort of healthy adults, showing effects from early adulthood and sex-specific patterns.

The paper performs a metabolome-wide association study to identify CSF metabolite-phenotype associations in neurological and psychiatric disorders.

The paper identifies CSF metabolites associated with tau levels and shows they improve prediction of Alzheimer's disease status.

This study examines the association between multiple self-reported health behaviors and cognitive decline in a cohort of non-demented middle-aged individuals, finding limited significant associations.

This study uses longitudinal amyloid PET data to estimate amyloid chronicity and finds it is linked to cognitive decline and tau burden in preclinical Alzheimer's disease.

The paper compares cognitive and hippocampal volume decline in asymptomatic adults with and without CSF β-amyloid or tau markers, finding accelerated decline in those with positive markers.

This study shows that hypertension and depression, but not obesity, moderate the link between amyloid and cognitive decline in midlife individuals at risk for Alzheimer's disease.

The paper reviews findings from the Wisconsin Registry for Alzheimer’s Prevention, highlighting associations between genetic and lifestyle factors and early AD pathophysiology.