Rebecca L. Koscik

The paper identifies seven metabolites associated with executive function decline in early Alzheimer’s disease using longitudinal plasma samples from the WRAP cohort.

The paper investigates if story recall of proper names is linked to beta-amyloid levels in cognitively unimpaired adults at risk for Alzheimer's disease, finding an association with delayed recall.

This study examines the association between multiple self-reported health behaviors and cognitive decline in a cohort of non-demented middle-aged individuals, finding limited significant associations.

This study uses longitudinal amyloid PET data to estimate amyloid chronicity and finds it is linked to cognitive decline and tau burden in preclinical Alzheimer's disease.

This study identifies age and sex-associated metabolite trajectories in longitudinal plasma samples from the WRAP cohort, revealing sex-specific changes in metabolites like sphingolipids and heritability patterns.

The paper uses information-theoretic model-averaging to analyze cognitive decline factors in mid-life, finding sex, literacy, and APOE ɛ4 effects with varying impacts.

The paper develops longitudinal standards for mid-life cognitive performance using quantile regression to identify abnormal within-person changes and their associations with clinical outcomes.

The paper compares cognitive and hippocampal volume decline in asymptomatic adults with and without CSF β-amyloid or tau markers, finding accelerated decline in those with positive markers.

This study shows that hypertension and depression, but not obesity, moderate the link between amyloid and cognitive decline in midlife individuals at risk for Alzheimer's disease.

The paper reviews findings from the Wisconsin Registry for Alzheimer’s Prevention, highlighting associations between genetic and lifestyle factors and early AD pathophysiology.

The paper uses longitudinal data to identify the temporal order of cognitive marker changes in Alzheimer’s disease, finding that digit span tests decline earliest followed by verbal memory and other tests.