Author

Marieke Griffioen

Leiden University Medical CenterORCID 0000-0002-3001-4441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Erik B. van den AkkeriD· 2 shared Akmal SalimoviD· 1 shared Alicia PerzolliiD· 1 shared Andrej LissatiD· 1 shared Angela F. El HebieshyiD· 1 shared Anneloes van der Plas - van DuijniD· 1 shared Bianca F. GoemansiD· 1 shared C. Michael Zwaan· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Erik B. van den AkkerORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 7, 2026

Spatial multi-omics reveals targetable immunosuppressive macrophage T-cell interactions in human AML bone marrow

Merel van der Meulen, Emma S. Pool, Alicia Perzolli…·Olaf T Heidenreich

This paper uses spatial multi-omics to identify immunosuppressive interactions between AML, macrophages, and T cells in bone marrow, highlighting the Galectin-9 - CD44/TIM-3 axis as a therapeutic target.

DOI 10.64898/2026.08.07.743431

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintAug 4, 2026

Human CEBPA-N AML exhibits enhanced engraftment and a C/EBPα-p30-driven leukemic stem cell program

Philomina Sona Peramangalam, Mayuresh Vishwas Konde, Emin Onur Karakaslar…·John Anto Pulikkan

This study identifies CEBPA-N-AML as having enhanced engraftment and defines a novel LSC signature in CEBPA-N-AML.

DOI 10.64898/2026.08.03.742558

humanflow cytometry

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ImmunologybioRxivPreprintDec 23, 2024

Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C.

Cilia R. Pothast, Ian Derksen, Anneloes van der Plas - van Duijn…·Ferenc A. Scheeren

The paper introduces a temperature-based peptide exchange method for loading different peptides into MHC-I multimers for HLA-A, B, and C alleles, enabling high-throughput T cell response analysis.

DOI 10.1101/2024.12.23.630039

humanCITE-seq

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