Author

Maria Kaukab Osman

University of FreiburgORCID 0000-0002-3003-0724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

Peter ReutheriD· 3 shared Christian SiebeniD· 2 shared Jonathan RobertiD· 2 shared Kevin CiminskiiD· 2 shared Lukas BroichiD· 2 shared Martin SchwemmleiD· 2 shared Antoni G. WrobeliD· 1 shared Dennis FrankiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

Peter ReutherORCID

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3 papers

Recent·Most cited

MHC-II acts as a fusion-triggering receptor for bat influenza virus

Sarah Peterl, Jonathan Robert, Maria Kaukab Osman, Rebecca A. Haines, Konstantin Fischer, Richard E Langi, Kevin Ciminski, Martin Schwemmle, Peter Reuther, Petr Chlanda

This study identifies MHC-II as a receptor that directly triggers membrane fusion for bat influenza virus H18N11, revealing a receptor-dependent mechanism distinct from conventional sialic acid receptor usage.

bioRxiv · Jul 9, 2026 · PreprintMicrobiology

Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface

Lukas Broich, Hannah Wullenkord, Maria Kaukab Osman, Yang Fu, Mathias Müsken, Peter Reuther, Mark Brönstrup, Christian Sieben

This study uses single-molecule microscopy to investigate influenza A virus-induced nanoscale cellular changes at the virus-cell interface, revealing receptor dynamics and actin cortex responses.

Nature Communications · Apr 25, 2025Peer-reviewedMicrobiology

The bat Influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment

Maria Kaukab Osman, Jonathan Robert, Lukas Broich, Dennis Frank, Robert Grosse, Martin Schwemmle, Antoni G. Wrobel, Kevin Ciminski, Christian Sieben, Peter Reuther

This study shows that bat influenza A virus H18N11 attaches to MHCII clusters on host cells, causing local clustering of MHCII molecules similar to immunological synapse formation.

Nature Communications · Apr 25, 2025Peer-reviewedMicrobiology