Antoni G. Wrobel

Mechanism of spike opening in a mammalian gammacoronavirus

This study reports the structures of a mammalian gamma-CoV spike in closed and open conformations, revealing conserved mechanisms of spike dynamics and lipid binding's role in stabilizing the closed state.

The bat Influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment

This study shows that bat influenza A virus H18N11 attaches to MHCII clusters on host cells, causing local clustering of MHCII molecules similar to immunological synapse formation.

The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

This paper identifies the V1H subunit of V-ATPase as a regulator of ATG16L1 recruitment in response to pH gradient disruption, linking V-ATPase function to autophagy activation.

Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retrovirus co-option

The paper identifies a novel ACE2 isoform, LTR16A1-ACE2, induced by interferon, which is non-functional and does not enhance SARS-CoV-2 infection.