Author

Kira J. Weissman

Centre National de la Recherche ScientifiqueORCID 0000-0002-3012-2960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:bacteria (other)· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Andrea CalderariiD· 2 shared Helge B. BodeiD· 2 shared Alicia Chateau· 1 shared Arnaud Bolard· 1 shared Arnaud GrueziD· 1 shared Bertrand AigleiD· 1 shared Carine Lombard· 1 shared Christophe JacobiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Andrea CalderariORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Total Biosynthesis of Pseudomonas aeruginosa-Derived Azabicyclocarbamates Identifies Distinct Dehydrating Condensation Family Proteins

Xiaohan Liu, Soumaya Najah, Andrea Calderari, Zhilai Hong, Sébastien Halary, Carine Lombard, Arnaud Bolard, Katy Jeannot, Arnaud Gruez, Kira J. Weissman, Yanyan Li

The paper identifies a new family of dehydrating condensation domain proteins involved in the biosynthesis of azabicyclocarbamates in Pseudomonas aeruginosa.

bioRxiv · Jul 17, 2026 · PreprintBiochemistry

Derivatization of the non-ribosomal peptide pyrrolizixenamide using NRPS engineering

Juliana Effert, Andrea Calderari, Susanna Kremer, Kira J. Weissman, Helge B. Bode

This study uses NRPS engineering to generate novel peptides with a pyrrolizixenamide moiety but finds that TE domain specificity limits further diversification.

bioRxiv · Jul 13, 2026 · PreprintBiochemistry

Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues

Ли Су, Souaibou Yaouba, Laurence Hôtel, Christophe Jacob, Peter Grün, Yan‐Ni Shi, Alicia Chateau, Sophie Pinel, Helge B. Bode, Bertrand Aigle, Kira J. Weissman

This paper uses mutasynthesis to generate stambomycin derivatives by engineering a bacterial strain and leveraging a promiscuous acyl transferase domain, resulting in new analogues with similar or reduced bioactivity.

Chemical Science · Jan 1, 2025Peer-reviewedSynthetic Biology