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Acyl amides derived from a bacterial symbiont control development of its nematode host

The paper identifies bacterial acyl amides, called stripteamides, as signals controlling nematode development in the Steinernema-Xenorhabdus symbiosis.

Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues

This paper uses mutasynthesis to generate stambomycin derivatives by engineering a bacterial strain and leveraging a promiscuous acyl transferase domain, resulting in new analogues with similar or reduced bioactivity.