Holly Holliday

This study uses single-cell RNA-sequencing and spatial transcriptomics to analyze epithelial and fibroblast states in hormone therapy-naive prostate cancer, identifying novel phenotypes and molecular perturbations.

This study shows that combining FACT and BET inhibition disrupts oncogenic transcription and extends survival in Diffuse Midline Glioma models.

The paper shows that L-proline drives mouse embryonic stem cells to become primitive-ectoderm-like cells through signaling pathway interactions.

This study identifies ID4 as a repressor of myoepithelial differentiation in mammary stem cells through its interaction with HEB, using integrated transcriptomic, proteomic, and ChIP-sequencing data.

This study identifies ID4's role in DNA damage response in BLBC and HGSOV by showing its interaction with MDC1 and DNA repair proteins, linking it to BRCA1-mutant tumors.