Author

Sofia Fertuzinhos

Yale UniversityORCID 0000-0002-3045-4201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angus Clark NairniD· 1 shared Aslam Abbasi Akhtar· 1 shared C. Danielle Antonuk· 1 shared Ernestine Giahyue· 1 shared Florine ColliniD· 1 shared G Kim· 1 shared J Molina· 1 shared Joshua J. BreunigiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Angus Clark NairnORCID

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2 papers

Recent·Most cited

Dynamin 2–dependent endocytosis differentially regulates ligand and receptor contributions to Notch signaling during neural precursor cell fate determination

Joshua J. Breunig, Juan I. Arellano, G Kim, K Anighoro, C. Danielle Antonuk, Rachelle Levy, Aslam Abbasi Akhtar, J Molina, Masato Torii, K Hashimoto-Torii, Sofia Fertuzinhos, Martin H. Dominguez, L Grigereit, Moise Danielpour, PASKO T. RAKIC

This study shows that dynamin 2 is essential for neural stem cell maintenance through its role in endocytosis, which differentially regulates Notch ligand and receptor activity.

bioRxiv · Jun 12, 2026 · PreprintDevelopmental Biology

mPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model

Zuhair I. Abdulla, Rolando Garcia-Milian, Ernestine Giahyue, Sofia Fertuzinhos, Florine Collin, Weiwei Wang, TuKiet T. Lam, Angus Clark Nairn, Marina R. Picciotto

The paper identifies proteomic changes in mPFC synaptosomes of mice exposed to inescapable stress, highlighting muscarinic receptor alterations and signaling pathway disruptions linked to depression.

eNeuro · Apr 1, 2026Peer-reviewedNeuroscience