Author

Manuel Tavares

Cancer Research UKORCID 0000-0002-3048-5331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ana Losada de la Lastra· 1 shared Christelle SoudyiD· 1 shared Cory A. OcasioiD· 1 shared Edward W. TateiD· 1 shared Elisabeth M. StorckiD· 1 shared Garima KhandelwaliD· 1 shared Goran TomićiD· 1 shared Jack W. HoughtoniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Ana Losada de la Lastra

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2 papers

Recent·Most cited

A palmitoyl transferase chemical genetic system to map ZDHHC-specific S-acylation

Cory A. Ocasio, Marc P. Baggelaar, James Sipthorp, Ana Losada de la Lastra, Manuel Tavares, Jana Volarić, Christelle Soudy, Elisabeth M. Storck, Jack W. Houghton, Susana Alejandra Palma-Duran, James I. MacRae, Goran Tomić, Lotte Carr, Julian Downward, Ulrike Eggert, Edward W. Tate

The paper introduces a chemical genetic system to map ZDHHC-specific S-acylation substrates at the whole proteome level in intact cells.

Nature Biotechnology · Jan 8, 2024Peer-reviewedMolecular Biology

JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation

Manuel Tavares, Garima Khandelwal, Joanne Muter, Keijo M. Viiri, Manuel Beltran-Nebot, Jan Joris Brosens, Richard G. Jenner

This study shows that JAZF1-SUZ12 fusion protein disrupts PRC2 function, leading to altered histone modifications and gene expression during cell differentiation.

Cell Reports · May 1, 2022Peer-reviewedMolecular Biology