Author

Zhi‐Cheng Yao

Johns Hopkins UniversityORCID 0000-0002-3086-6038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Bobby Y.X. NiiD· 2 shared Hai‐Quan MaoiD· 2 shared Jessica L. StelzeliD· 2 shared Joshua C. DoloffiD· 2 shared Kailei D. GoodieriD· 2 shared Sashank ReddyiD· 2 shared Bryan L. McCartyiD· 1 shared Christine Y. WeiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBioengineering

Bobby Y.X. NiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Fibroblast signaling influences macrophage-dependent, biomaterial-induced tissue remodeling

Jessica L. Stelzel, Stuart J. Bauer, B. Ni, Zhi‐Cheng Yao, Victor M. Quiroz, Jamie L. Hernandez, Bryan L. McCarty, Russell A. Martin, Kailei D. Goodier, V.W.K. Wong, Sashank Reddy, Hai‐Quan Mao, Joshua C. Doloff

This study identifies fibroblast-macrophage signaling as critical for biomaterial-induced tissue remodeling, revealing prolonged inflammation and novel cell types involved.

bioRxiv · Apr 28, 2026 · PreprintBioengineering

mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy

Yining Zhu, Zhi‐Cheng Yao, S.-H. Li, Jingyao Ma, Christine Y. Wei, Di Yu, Jessica L. Stelzel, Bobby Y.X. Ni, Yang Miao, Kyra Van Batavia, Xiaoya Lu, Jinghan Lin, Yifan Dai, Jiayuan Kong, Ruochen Shen, , Hai‐Quan Mao

The paper develops a nanofiber-hydrogel composite incorporating mRNA lipid nanoparticles to create a local immunostimulatory niche for cancer immunotherapy, showing enhanced immune responses with a single dose.

bioRxiv · Jan 27, 2025 · PreprintBioengineering