Author

S.-H. Li

Johns Hopkins UniversityORCID 0000-0002-9832-9159Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

S.-H. Li1 paper

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Christine Y. WeiiD· 2 shared Hai‐Quan MaoiD· 2 shared Jinghan LiniD· 2 shared Jingyao MaiD· 2 shared Jonathan P. SchneckiD· 2 shared Joseph ChoyiD· 2 shared Kailei D. GoodieriD· 2 shared Xiang LiuiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Christine Y. WeiORCID

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2 papers

Recent·Most cited

Systemic trafficking of mRNA lipid nanoparticle vaccine following intramuscular injection generates potent tissue-specific T cell response

Christine Y. Wei, Yining Zhu, Xiaoya Lu, Kailei D. Goodier, Di Yu, Xiang Liu, Joseph Choy, Alejandro Téllez Calderón, Jingyao Ma, Yunhe Su, Jinghan Lin, S.-H. Li, Jonathan P. Schneck, Sean C. Murphy, Hai‐Quan Mao

This study shows that mRNA lipid nanoparticles (LNPs) can be tailored to traffic to specific organs, enhancing tissue-specific T cell responses and vaccine efficacy.

bioRxiv · Apr 21, 2025 · PreprintBioengineering

mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy

Yining Zhu, Zhi‐Cheng Yao, S.-H. Li, Jingyao Ma, Christine Y. Wei, Di Yu, Jessica L. Stelzel, Bobby Y.X. Ni, Yang Miao, Kyra Van Batavia, Xiaoya Lu, Jinghan Lin, Yifan Dai, Jiayuan Kong, Ruochen Shen, , Hai‐Quan Mao

The paper develops a nanofiber-hydrogel composite incorporating mRNA lipid nanoparticles to create a local immunostimulatory niche for cancer immunotherapy, showing enhanced immune responses with a single dose.

bioRxiv · Jan 27, 2025 · PreprintBioengineering