Author

Serena Tamura

University of California, San FranciscoORCID 0000-0002-3090-2385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew D. NelsoniD· 1 shared Atehsa SahaguniD· 1 shared Beniamin KrupkiniD· 1 shared Caroline M. Keeshen· 1 shared Coline ArnouldiD· 1 shared Congyi LuiD· 1 shared Elizabeth C. HamadaiD· 1 shared Henry KyoungiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Andrew D. NelsonORCID

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1 paper

Recent·Most cited

CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder

Serena Tamura, Andrew D. Nelson, Perry W.E. Spratt, Elizabeth C. Hamada, Xujia Zhou, Henry Kyoung, Zizheng Li, Coline Arnould, Vladyslav Barskyi, Beniamin Krupkin, Kiana Young, Jingjing Zhao, Stephanie S. Holden, Atehsa Sahagun, Caroline M. Keeshen, , Kevin J. Bender

This study shows that CRISPR activation can rescue electrophysiological deficits in SCN2A haploinsufficiency by increasing the expression of the remaining functional allele in mice and human neurons.

Nature · Sep 17, 2025Peer-reviewedNeuroscience