Matthieu Defrance

USP7/Maged1-Mediated H2A Monoubiquitination in the Paraventricular Thalamus: An Epigenetic Mechanism Involved in Cocaine Use Disorder

RedRibbon: A new rank-rank hypergeometric overlap pipeline to compare gene and transcript expression signatures

RedRibbon is a rank-rank hypergeometric overlap method for comparing gene and transcript expression signatures, showing accuracy and efficiency on large datasets.

Facing lethal temperatures: heat shock response in desert and temperate ants

The paper compares the transcriptomic heat stress responses of desert and temperate ants to identify convergent and specific adaptations to thermal stress.

Explainability methods for differential gene analysis of single cell RNA-seq clustering models

The paper compares differential expression methods for scRNA-seq clustering models, finding gradient-based methods outperform traditional approaches.

Optimization algorithm for omic data subspace clustering

The paper introduces a method for subspace clustering of omic data and shows it outperforms existing techniques in identifying ground-truth subspaces.

TIGER: The gene expression regulatory variation landscape of human pancreatic islets

The paper creates TIGER, a resource integrating RNA-seq and genotyping data from human pancreatic islets to identify eQTLs and their associations with type 2 diabetes.

Combining single-cell RNA-sequencing with a molecular atlas unveils new markers for C. elegans neuron classes.

The paper combines scRNA-seq with a molecular atlas to identify new neuron class markers in C. elegans, assigning 58 clusters to known neuron classes and validating 15 new promoters.

Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo

The paper shows that mesoderm cells in embryonic and extra-embryonic regions of the mouse embryo have distinct migration behaviors and cytoskeleton regulation.