This study investigates the role of AhR in mediating pulmonary responses to cannabis smoke, finding that AhR activation reduces inflammation and tissue remodeling in the lungs.

The FASEB Journal · Sep 17, 2025Peer-reviewedPharmacology & Toxicology

AB-free kava enhances resilience against the adverse health effects of tobacco smoke in mice

Tengfei Bian, Allison M. Lynch, Kayleigh Ballas, Jessica Mamallapalli, Breanne Freeman, Alexander Scala, Yifan Wang, Hussein Traboulsi, Ranjith kumar Chellian, Amy Fagan, Zhixin Tang, Haocheng Ding, Umasankar De, Kristianna M. Fredenburg, Zhiguang Huo, , Chengguo Xing

This study evaluates AB-free kava's effects on tobacco smoke-exposed mice, showing it mitigates health deficits with safety, suggesting potential for reducing tobacco-related harm.

ACS Pharmacology & Translational Science · Oct 2, 2024Peer-reviewedPharmacology & Toxicology

DENetwork: Unveiling Regulatory and Signaling Networks Behind Differentially-Expressed Genes

Ting‐Yi Su, Quazi S. Islam, Steven Kenneth Huang, Carolyn J. Baglole, Jun Ding

DENetwork identifies regulatory and signaling networks behind differentially-expressed genes by integrating DE and non-DE genes in a graphical model, enhancing traditional differential gene analysis.

bioRxiv · Jun 27, 2023 · PreprintBioinformatics

Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light

Babak Memari, Loan Nguyen‐Yamamoto, Reyhaneh Salehi-Tabar, Michela Zago, Jorg H. Fritz, Carolyn J. Baglole, David Goltzman, John H. White

This study shows that moderate UVB exposure induces AHR signaling in multiple organs, suggesting endocrine control of immunity through AHR.

Scientific Reports · Jun 11, 2019Peer-reviewedMolecular Biology