Author

Breanne Freeman

University of FloridaORCID 0009-0004-2416-1535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Chengguo XingiD· 3 shared Adriaan W. BruijnzeeliD· 2 shared Allison M. Lynch· 2 shared Leah R. ReznikoviD· 2 shared Tengfei BianiD· 2 shared Weizhou ZhangiD· 2 shared Alexander Scala· 1 shared Amy Fagan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

Chengguo XingORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 25, 2026

AB-Free Kava and its Kavalactones Suppress Cigarette Smoke- and Lipopolysaccharide-Induced Lung Inflammation: Efficacy and Mechanisms

Gujie Xu, Tengfei Bian, Breanne Freeman…·Chengguo Xing

This study identifies bioactive kavalactones in AB-free kava that suppress lung inflammation via PKA/CREB/COX-2 signaling, offering a new therapeutic approach for smoke-induced pulmonary diseases.

DOI 10.64898/2026.08.21.746215

mouseproteomics

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Cancer BiologyChemical Research in ToxicologyPeer-reviewedSep 3, 2025

An LC-MS/MS method for the quantification of tobacco-specific carcinogen protein adducts.

Breanne Freeman, Chengguo Xing

The paper develops an LC-MS/MS method to quantify NNAL-specific protein adducts in biological samples to assess tobacco exposure and estimate NNAL bioactivation.

1 citation

proteomicsexperimental assay

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Pharmacology & ToxicologyACS Pharmacology & Translational SciencePeer-reviewedOct 2, 2024

AB-free kava enhances resilience against the adverse health effects of tobacco smoke in mice

Tengfei Bian, Allison M. Lynch, Kayleigh Ballas…·Chengguo Xing

This study evaluates AB-free kava's effects on tobacco smoke-exposed mice, showing it mitigates health deficits with safety, suggesting potential for reducing tobacco-related harm.

6 citations

mousebulk RNA-seq

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