Barry M. Zee

This study shows that targeting SAGA/ATAC complexes disrupts chromatin regulation and cholesterol metabolism in diffuse midline glioma, leading to reduced tumor growth.

This study identifies elongin B as a key regulator of Pol2 elongation in H3K27M-mutant diffuse midline glioma, showing its role in maintaining chromatin and transcriptional dysregulation.

This study identifies numerous post-translational modification sites using immunoaffinity enrichment and nDIA mass spectrometry, showing nDIA's superior coverage and efficiency.

The paper quantifies UFMylation sites in mouse tissues and ALS patient biopsies, finding increased myosin UFMylation in ALS.

The paper shows that BRD4-NUT fusion protein creates chromatin megadomains whose locations depend on the initial cell state, not genetic variation.

The paper identifies variant Polycomb complexes in Drosophila, supporting their ancient functional diversity through proteomic analyses.