Matthew P. Stokes

This study identifies numerous post-translational modification sites using immunoaffinity enrichment and nDIA mass spectrometry, showing nDIA's superior coverage and efficiency.

The paper quantifies UFMylation sites in mouse tissues and ALS patient biopsies, finding increased myosin UFMylation in ALS.

This study identifies ATM's role in regulating vesicular protein secretion through CHGA and microtubule dynamics via CRMP5 in neurons, linking A-T neural atrophy to growth cone collapse.

This study identifies FAK's role in regulating cAMP levels in osteocytes through PDE8A, showing FAK inhibition increases cAMP and downstream signaling.

The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.

This study develops a rodent model of rotational head trauma, identifies Cdk5 as a key mediator, and shows its inhibition reduces cognitive and pathological effects.

The paper investigates how PTPRD expression levels affect phosphotyrosine phosphoproteomic profiles in young and aged mice brains, identifying potential substrates and functional implications.

The paper characterizes lysine acetylation in the human gut microbiome and identifies differential acetylation patterns in Crohn’s disease patients.