Dissecting Gap Junctional and Ephaptic Contributions to Electrical Conduction in a Novel Cardiomyocyte Pair Model
Xiaobo Wu, Sharon A. Swanger, Linnea Elisabeth Bornkast Meier, Clare L. Dennison, Seth H. Weinberg, Steven Poelzing, Robert G. Gourdie
This paper develops a novel cardiomyocyte pair model to quantify gap junction and ephaptic contributions to electrical conduction, showing that ephaptic mechanisms dominate at physiological sodium levels.
bioRxiv · Mar 6, 2026 · PreprintBiophysics