Sharon A. Swanger

This study investigates the role of GluN2D-containing NMDA receptors in dentate granule cells, showing their importance in excitability, synaptic plasticity, and spatial memory.

This paper develops a novel cardiomyocyte pair model to quantify gap junction and ephaptic contributions to electrical conduction, showing that ephaptic mechanisms dominate at physiological sodium levels.

This study examines synapse function in thalamic regions of Dravet syndrome mice before, during, and after seizures, revealing persistent input- and cell-type-specific synaptic deficits in adulthood.

The paper compares mitochondrial morphology and function in hippocampal CA1 and CA2 circuits, finding cell-type and input-specific differences that may influence circuit properties and disease vulnerability.

This study investigates how hypernatremia affects action potential duration in a mouse model of long QT syndrome type 3, finding that it increases transient outward potassium currents and alters repolarization patterns.

The paper uses multiplexed smFISH to analyze the spatial organization of 15 synaptic neuropil localized mRNAs in rodent hippocampus, finding that colocalization patterns scale with mRNA abundance.

This study investigates the input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons using super resolution imaging and knockout-validated antibodies.

This study compares synaptic and intrinsic properties of VPL and VPM thalamus neurons in mice, finding functional differences in their excitatory and inhibitory inputs and firing behavior.

This paper investigates how NaV1.1 haploinsufficiency affects thalamocortical circuit function in a Dravet syndrome mouse model, revealing input-specific synaptic and intrinsic changes in thalamic neurons.