Author

Dahyun Yu

University of MinnesotaORCID 0000-0002-3179-4080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Gülin ÖziD· 2 shared Katherine GundryiD· 2 shared Leonard PetrucelliiD· 2 shared Nicole ZarateiD· 2 shared Rocío Gómez‐PastoriD· 2 shared Alfonso AraqueiD· 1 shared Aliza P. WingoiD· 1 shared Anantharaman ShantaramaniD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Gülin ÖzORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 28, 2026

Progranulin deficiency perturbs lipid metabolism in white matter microglia

Dahyun Yu, Ellen Armour, Sonnet S. Davis…·Leonard Petrucelli

This study shows that PGRN deficiency in microglia affects lipid metabolism, including reduced BMP and PE and increased GalCer, with age-dependent changes in Grn KO mice.

DOI 10.64898/2026.07.27.740601

mousestatistical model

Cell BiologybioRxivPreprintMar 28, 2026

Neurodegeneration risk variants promote lysosomal TMEM106B fibrilaccumulation

John Michael Replogle, Jordan D. Marks, Martin G. Fernandez…·Michael Emmerson Ward

The paper identifies TMEM106B fibril accumulation as a shared mechanism in neurodegeneration linked to genetic variants in TMEM106B and GRN.

3 citations

mousehuman

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJun 3, 2022

CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease

Dahyun Yu, Nicole Zarate, Angel White…·Rocío Gómez‐Pastor

This study shows that reducing CK2 in HD mice improves neuroinflammation, HTT aggregation, and motor deficits by reducing synucleinopathy.

29 citations

mousebulk RNA-seq

NeurosciencebioRxivPreprintOct 26, 2021

In vivo MR spectroscopy reflects synapse density in a Huntington's disease mouse model

Nicole Zarate, Katherine Gundry, Dahyun Yu…·Rocío Gómez‐Pastor

This study links in vivo 1H-MRS neurochemical changes to specific synaptic pathway alterations in a Huntington's disease mouse model.

1 citation

mousestatistical model