BetaII-Spectrin Gaps and Patches Emerge from the Patterned Assembly of the Actin/Spectrin Membrane Skeleton in Human Motor Neuron Axons
Nahir Guadalupe Gazal, María José Castellanos‐Montiel, Guillermina Bruno, Anna Kristina Franco-Flores, Sarah Lépine, Lale Gursu, Ghazal Haghi, Gilles Maussion, Wolfgang Reintsch, Fernando Daniel Stefani, Agustín Anastasía, Mariano Bisbal, Ezequiel Axel Gorostiza, Thomas M. Durcan, Nicolás Unsain
The paper uses imaging to study the spatial distribution of betaII-spectrin in human motor neuron axons, revealing a gap-and-patch pattern in the actin/spectrin membrane skeleton.
eLife · Sep 8, 2026Peer-reviewedNeuroscience