Author

Mark J. Yeager

University of MiamiORCID 0000-0002-3301-640XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Gregory A. VothiD· 2 shared Arpa HudaitiD· 1 shared Brian D. Adair· 1 shared Clary B. ClishiD· 1 shared Conroy O. FieldiD· 1 shared David A. TessiD· 1 shared Donald W. LandryiD· 1 shared Eivgeni Mashin· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

Gregory A. VothORCID

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3 papers

Recent·Most cited

Mechanism of Phosphatidylserine Lipid Scrambling by Human SERINC3, an HIV-1Restriction Factor

Puja Banerjee, Mark J. Yeager, Gregory A. Voth

This study investigates the mechanism of phosphatidylserine scrambling by hSERINC3 using simulations, revealing a novel 'credit card' mechanism distinct from classical models.

bioRxiv · Nov 13, 2025 · PreprintBiophysics

Kinetic Implications of IP6 Anion Binding on the Molecular Switch of the HIV-1 Capsid Assembly

Manish Gupta, Arpa Hudait, Mark J. Yeager, Gregory A. Voth

This study shows IP6 binding influences the kinetic switch of the HIV-1 capsid's TVGG motif between coil and helix conformations, essential for pentamer formation.

Science Advances · Apr 16, 2025Peer-reviewedBiophysics

Platelet integrin αIIbβ3 plays a key role in venous thrombogenesis in a mouse model

Brian D. Adair, Conroy O. Field, José L. Alonso, Jian-Ping Xiong, Shi‐Xian Deng, Hyun-Sook Ahn, Eivgeni Mashin, Clary B. Clish, Johannes F. Van Agthoven, Mark J. Yeager, Youzhong Guo, David A. Tess, Donald W. Landry, Mortimer Poncz, M. Amin Arnaout

This paper shows that m-tirofiban, a non-partial agonist of IIbβ3, effectively inhibits venous thrombosis without increasing bleeding in a mouse model.

Nature Communications · Oct 4, 2024Peer-reviewedPathology