Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision
Ludovica Ciampi, Federica Mantica, Laura López-Blanch, Jon Permanyer, Cristina Rodríguez-Marin, Jingjing Zang, Damiano Cianferoni, Senda Jiménez‐Delgado, Sophie Bonnal, Samuel Miravet‐Verde, Verena Ruprecht, Stephan C. F. Neuhauss, Sandro Banfi, Sabrina Carrella, Luis G. Serrano, , Manuel Irimia
The paper identifies Srrm3-dependent microexons as critical for photoreceptor function and vision, showing their role in outer segment maintenance and their loss leading to blindness.
Proceedings of the National Academy of Sciences · Jul 12, 2022Peer-reviewedSystems Biology