Jonathan J. Augustin

The paper provides a high-resolution molecular and cellular analysis of Broca's area and motor cortex across developmental stages, identifying distinct cellular signatures and vulnerabilities to neurodevelopmental disorders.

This paper introduces vascularized cortical assembloids (vCAs) that model neurovascular co-development and show improved cellular specialization and connectivity compared to standard cortical organoids.

This study maps the molecular and cellular dynamics of the developing human neocortex using single-nucleus data, revealing gene regulatory networks and a cancer-related progenitor subtype.

This study identifies Pantr2 as a trans-acting lncRNA that regulates gene expression and chromatin accessibility, affecting neural progenitor differentiation through Notch and Wnt signaling disruption.

The paper introduces tricycle, a method to predict cell cycle position from single-cell RNA-seq data using transfer learning, showing it generalizes across datasets and species.

This study investigates the effects of KMT2D loss in brain cell development, finding precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome models.