Author
German Cancer Research CenterORCID 0000-0002-3315-305XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Charles S. Umbaugh, Marie Groth, Cihan Erkut…·Claudia Scholl
This study uses T-DARPins to inhibit TBXT in chordoma cells, revealing its regulome and identifying therapeutic vulnerabilities, including sensitivity to JAK2 inhibitors.
Nils Eickhoff, Janina Janetzko, Nuno Padrão…·Wilbert T. Zwart
The paper shows TRIM33 enhances AR activity by reducing H2BK120 ubiquitination, without affecting AR protein stability.
Sylvan C. Baca, Cassandra Singler, Soumya Zacharia…·Matthew L. Freedman
The paper introduces CWAS, a method linking genetic variation to chromatin states, identifying novel prostate cancer risk loci and regulatory mechanisms not detectable by eQTLs.
Anna G. Manjón, Simon Linder, Hans Teunissen…·René H. Medema
This study reports that lentiviral-based CRISPR-Cas9 vectors can integrate into the target genomic location, unexpectedly activating the target gene.