Author

Asli Kayserili

German Cancer Research CenterORCID 0009-0002-0737-0664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreas PlückthuniD· 1 shared Birgit DreieriD· 1 shared Charles S. UmbaughiD· 1 shared Cihan ErkutiD· 1 shared Claudia ScholliD· 1 shared Dominic HelmiD· 1 shared Florian IseriD· 1 shared Joana MarinhoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andreas PlückthunORCID

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1 paper

Recent·Most cited

Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma

Charles S. Umbaugh, Marie Groth, Cihan Erkut, Kwang-Seok Lee, Joana Marinho, Simon Linder, Florian Iser, Jonas N. Kapp, Petra Schroeter, Simay Dolaner, Asli Kayserili, Dominic Helm, Martin Schneider, Julia Hartmann, Philipp Walch, , Claudia Scholl

This study uses T-DARPins to inhibit TBXT in chordoma cells, revealing its regulome and identifying therapeutic vulnerabilities, including sensitivity to JAK2 inhibitors.

Science Advances · Sep 3, 2025Peer-reviewedCancer Biology