Adam I. Ramsaran

Delayed maturation of hippocampal trisynaptic circuitry underlies the protracted development of episodic-like memory

This study shows that delayed maturation of trisynaptic hippocampal circuitry is essential for the development of high-resolution episodic-like memory in mice.

Activity-dependent myelination in prefrontal circuits signals the offset of infantile amnesia

The paper shows that activity in the prelimbic cortex of developing mice promotes myelination and memory persistence, delaying infantile amnesia when inhibited.

Distinct CA1 inputs support shifts in neural dimensionality and memory resolution

The paper shows that distinct inputs to the CA1 region of the hippocampus support different memory resolutions by altering neural dimensionality and feedforward inhibition.

A sensitive period for the development of episodic-like memory in mice

This study shows that early-life experiences during a sensitive period influence the timing of episodic-like memory development in mice by modulating perineuronal net formation.

A shift in the mechanisms controlling hippocampal engram formation during brain maturation

This study shows that the maturation of hippocampal inhibitory interneurons by extracellular matrix is necessary for the development of precise episodic-like memories in mice.

Evolution of predictive memory in the hippocampus

This study shows how hippocampal activity supports building predictive models by organizing newly learned information according to its congruence with existing memories.

Automated curation of CNMF-E-extracted ROI spatial footprints and calcium traces using open-source AutoML tools

The paper introduces an automated curation method for CNMF-E-extracted ROIs and calcium traces using TPOT and AutoSklearn, achieving an F1 score > 92% on a test dataset.

A compact head-mounted endoscope for in vivo calcium imaging in freely-behaving mice

This paper describes the construction and use of a low-cost, open-source head-mounted endoscope for in vivo calcium imaging in freely-behaving mice.