Cancer BiologybioRxivPreprint
Tumour rewires host tryptophan metabolism to promote organism-wide immune suppression
Lucia García-López, Ernesto Saez-Carrion, Mary Luz Uribe…·María Domínguez
This study shows that Pten-deficient Drosophila tumours reprogram host tryptophan metabolism to suppress immunity and promote tumour growth through the kynurenine pathway.
DOI 10.64898/2026.09.02.748262