Author

Imane Nait Irahal

InsermORCID 0000-0002-3330-6247Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Damien ArnoultiD· 2 shared Kelly Walsh· 1 shared Mingchong YangiD· 1 shared Mostafa KabineiD· 1 shared Saad HarriziiD· 1 shared Wen LiuiD· 1 shared Xiaoyan GuoiD· 1 shared Zengshuo Mo· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBioinformatics

Damien ArnoultORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 24, 2026

Gene identity, not variant effect, dominates ClinVar benchmarks of missense pathogenicity predictors

Saad Harrizi, Imane Nait Irahal, Mostafa Kabine, Damien Arnoult

The paper evaluates missense pathogenicity predictors using ClinVar data, finding that gene identity, not variant effect, largely drives benchmark performance.

DOI 10.64898/2026.08.21.746180

humanDNA methylation

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Cell BiologyNature CommunicationsPeer-reviewedApr 9, 2026

The Integrated Stress Response Suppresses PINK1-dependent Mitophagy by Preserving Mitochondrial Import Efficiency

Mingchong Yang, Zengshuo Mo, Kelly Walsh…·Xiaoyan Guo

This study shows the integrated stress response (ISR) suppresses mitophagy by maintaining mitochondrial import efficiency, independent of ATF4, under non-depolarizing stress.

17 citationstop 1%

proteomicsexperimental assay

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