Author

Ikuo Nobuhisa

Tokyo Medical and Dental UniversityORCID 0000-0002-3335-7714Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Tetsuya TagaiD· 2 shared Akiko Hayashi‐TakagiiD· 1 shared Akinobu MatsumotoiD· 1 shared Akio KiharaiD· 1 shared Akito NakaoiD· 1 shared Anja UrbachiD· 1 shared Atsuko Hayata‐TakanoiD· 1 shared Atsushi IwamaiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Tetsuya TagaORCID

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2 papers

Recent·Most cited

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, Mikio Hoshino, Akito Nakao, Yasuo Mori, Shigeo Okabe, Masayuki Matsushita, , Michihiro Igarashi

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

eLife · Sep 1, 2023Peer-reviewedNeuroscience

Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo

Gerel Melig, Ikuo Nobuhisa, Kiyoka Saito, Ryota Tsukahara, Ayumi Itabashi, Yoshiakira Kanai, Masami Kanai‐Azuma, Mitsujiro Osawa, Motohiko Oshima, Atsushi Iwama, Tetsuya Taga

This study identifies Rasip1 as a downstream target of Sox17 that enhances hematopoietic activity in intra-aortic hematopoietic clusters of midgestation mouse embryos.

bioRxiv · Nov 1, 2022 · PreprintDevelopmental Biology