Author

Xinyang Yu

University at Buffalo, State University of New YorkORCID 0000-0002-3341-0183Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1

Frequent Co-Authors

Michael Joseph BuckiD· 2 shared Anastasiia OnyshchenkoiD· 1 shared Brian D. SlaughteriD· 1 shared Jay R. UnruhiD· 1 shared Jeffrey J. LangeiD· 1 shared Julia ZeitlingeriD· 1 shared Kaelan BrennaniD· 1 shared Malini NatarajaniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Michael Joseph BuckORCID

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2 papers

Recent·Most cited

Lola-I is a developmentally regulated promoter pioneer factor

Vivekanandan Ramalingam, Xinyang Yu, Brian D. Slaughter, Jay R. Unruh, Kaelan Brennan, Anastasiia Onyshchenko, Jeffrey J. Lange, Malini Natarajan, Michael Joseph Buck, Julia Zeitlinger

The paper shows that Lola-I, a Drosophila zinc finger transcription factor, regulates promoter accessibility and paused Pol II during development, similar to enhancer regulation by pioneer factors.

bioRxiv · Apr 25, 2022 · PreprintGenomics

Defining p53 pioneering capabilities with competitive nucleosome binding assays

Xinyang Yu, Michael Joseph Buck

This study investigates p53's ability to bind nucleosomal DNA through competitive binding assays, showing it binds primarily at nucleosome edges with non-specific binding facilitating its pioneering function.

Genome Research · Jan 1, 2019Peer-reviewedGenomics