Anastasiia Onyshchenko

Lola-I is a developmentally regulated promoter pioneer factor

The paper shows that Lola-I, a Drosophila zinc finger transcription factor, regulates promoter accessibility and paused Pol II during development, similar to enhancer regulation by pioneer factors.

The genome of a nonphotosynthetic diatom provides insights into the metabolic shift to heterotrophy and constraints on the loss of photosynthesis

The paper sequenced the genome of a nonphotosynthetic diatom to understand metabolic changes after losing photosynthesis and found key genetic constraints and alternative pathways for energy acquisition.

Sphingolipid Biosynthesis Inhibition As A Host Strategy Against Diverse Pathogens

This study identifies that multiple cationic amphipathic drugs (CADs) share molecular similarities with chloroquine and inhibit sphingolipid biosynthesis, suggesting their potential as antiviral agents against diverse pathogens including SARS-CoV-2.

A single loss of photosynthesis in diatoms

The paper investigates the evolutionary loss of photosynthesis in diatoms, finding evidence for a single loss event supported by genomic and phylogenetic analyses.