Hematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic hemogenic endothelium
Joey J. Ghersi, Gabriel Baldissera, Jared Hintzen…·Stefania Nicoli
This study shows that miR-128 regulates HSPC heterogeneity by modulating Wnt and Notch signaling in hemogenic endothelium, leading to lineage-specific biases in zebrafish and human systems.