Author

Kendra J. Lechtenberg

Denali Therapeutics (United States)ORCID 0000-0002-3344-1289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alanna DorseyiD· 1 shared Amy W. Leung· 1 shared Andrew J. GentlesiD· 1 shared Darren Chan· 1 shared David A. JoyiD· 1 shared David Huynh· 1 shared Elysia Roche· 1 shared Emmanuel S. Ojo· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alanna DorseyORCID

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2 papers

Recent·Most cited

Transferrin receptor-mediated transport at the blood-brain barrier is elevated in early development but maintained across adult aging

Vanessa O. Torres, Michelle E. Pizzo, Darren Chan, Jason C. Dugas, David Huynh, David A. Joy, Eric Liang, Lily Sarrafha, Isabel A. Becerra, Roni Chau, Kylie S. Chew, Johann Chow, Timothy Earr, Nathalie Khoury, Kendra J. Lechtenberg, , Y. Joy Yu Zuchero

This study investigates TfR-mediated BBB transport in mice across development and aging, finding elevated transport in early development and stability across adulthood, including in an AD model.

bioRxiv · Nov 12, 2024 · PreprintNeuroscience

Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke

Victoria G. Hernandez, Kendra J. Lechtenberg, Todd C. Peterson, Li Zhu, Tawaun A. Lucas, Karen P. Bradshaw, Justice O. Owah, Alanna Dorsey, Andrew J. Gentles, Marion S. Buckwalter

The paper analyzes the translatome of astrocytes and microglia after stroke to identify their distinct roles in inflammation during hyperacute and acute phases.

Glia · Apr 17, 2023Peer-reviewedNeuroscience