Marion S. Buckwalter

This study shows that stroke increases hippocampal neurogenesis but leads to maladaptive morphological features in newborn neurons across multiple mouse stroke models.

The paper identifies a plasma proteomic signature linked to blood-brain barrier dysfunction, which predicts cognitive decline after ischemic stroke.

This study evaluates cognitive outcomes after stroke in mice using multiple models and tests, finding inconsistent results and highlighting challenges in pre-clinical stroke cognition research.

This paper uses VINE-seq to create a vascular transcriptomic atlas in Alzheimer's disease, revealing transcriptional changes in vascular cells and identifying angiopoietin signaling as a key dysregulated pathway.

This study shows that blocking VCAM1 or VLA4 after stroke preserves vascular integrity and prevents cognitive decline by promoting blood vessel growth and restoring the blood-brain barrier.

The paper identifies CD72 as a regulator of microglial tiling through proteomic profiling and functional assays.

This study develops a mouse model of pediatric ischemic stroke showing delayed cognitive decline and chronic neuroinflammation in uninjured brain regions in juvenile mice.

This study shows that TREM1 deficiency prevents age-related myeloid metabolic changes and cognitive decline in Alzheimer's disease models.

The paper shows that blocking TIC cytokines reduces neurotoxic astrocyte formation, leading to less brain damage and better recovery after stroke.

The paper analyzes the translatome of astrocytes and microglia after stroke to identify their distinct roles in inflammation during hyperacute and acute phases.

The paper identifies spleen glia as a unique glial subtype that interacts with both sympathetic axons and immune cells through specific gene expression.