Author

Karen P. Bradshaw

Stanford MedicineORCID 0000-0002-0338-7672Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

Marion S. BuckwalteriD· 3 shared Kristy A. ZeraiD· 2 shared Li ZhuiD· 2 shared Todd C. PetersoniD· 2 shared Tony Wyss‐CorayiD· 2 shared Alanna DorseyiD· 1 shared Andreas KelleriD· 1 shared Andrew C. YangiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Marion S. BuckwalterORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Angiopoietin signalling is a central axis of amyloid-driven vascular dysfunction in Alzheimer's disease

Matthias Flotho, Andrew C. Yang, Fabian Kern, Simon Graf, Ian Ferenc Diks, Heather Shin, Kristy A. Zera, Daniela Berdnik, Maayan R. Agam, Divya Channappa, Sophia M. Shi, Malia A. Belnap, Epiphani Simmons, Karen P. Bradshaw, Friederike Grandke, , Tony Wyss‐Coray

This paper uses VINE-seq to create a vascular transcriptomic atlas in Alzheimer's disease, revealing transcriptional changes in vascular cells and identifying angiopoietin signaling as a key dysregulated pathway.

bioRxiv · Aug 25, 2025 · PreprintNeuroscience

Blockade of VCAM1 or VLA4 preserves cerebrovasculature and prevents cognitive decline late after stroke

Kristy A. Zera, Karen P. Bradshaw, Li Zhu, Oliver Hahn, Aulden G. Foltz, Todd C. Peterson, Hanadie Yousef, Davis P. Lee, Elizabeth W. Mayne, Nima Aghaeepour, Tony Wyss‐Coray, Marion S. Buckwalter

This study shows that blocking VCAM1 or VLA4 after stroke preserves vascular integrity and prevents cognitive decline by promoting blood vessel growth and restoring the blood-brain barrier.

bioRxiv · Jun 25, 2025 · PreprintNeuroscience

Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke

Victoria G. Hernandez, Kendra J. Lechtenberg, Todd C. Peterson, Li Zhu, Tawaun A. Lucas, Karen P. Bradshaw, Justice O. Owah, Alanna Dorsey, Andrew J. Gentles, Marion S. Buckwalter

The paper analyzes the translatome of astrocytes and microglia after stroke to identify their distinct roles in inflammation during hyperacute and acute phases.

Glia · Apr 17, 2023Peer-reviewedNeuroscience