Author

Eric Liang

Denali Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Jason C. DugasiD· 3 shared Johann ChowiD· 3 shared Darren Chan· 2 shared David A. JoyiD· 2 shared David Huynh· 2 shared Elysia Roche· 2 shared Hilda O. SolanoyiD· 2 shared Hoang Ngan NguyeniD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Jason C. DugasORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lysosomes cell autonomously regulate myeloid cell states and immune responses

Leon Tejwani, Catherine M Heffner, Christopher D. Balak, Lukas L. Skuja, David Tatarakis, Anil Rana, Seungyoon B. Yu, Gabriel A. Fitzgerald, Connie Ha, Gabrielly Lunkes de Melo, Elizabeth Wen Sun, Matthew J. Simon, Jason C. Dugas, Johann Chow, Elliot R. Thomsen, , Gilbert Di Paolo

This study shows lysosomal health influences myeloid cell states and immune responses, with Grn deficiency leading to lysosomal dysfunction and specific transcriptional changes in microglia.

Immunity · Aug 1, 2026Peer-reviewedNeuroscience

Dual targeting of transferrin receptor and CD98hc enhances brain exposure of large molecules

Robert C. Wells, Padma Akkapeddi, Darren Chan, David A. Joy, Arash Moshkforoush, Roni Chau, Johann Chow, Gerald Maxwell Cherf, Ellen Y. T. Chien, Allisa J. Clemens, Michelle E. Pizzo, Ahlam N. Qerqez, Tiffany M. Tran, Isabel A. Becerra, Jason C. Dugas, , Kylie S. Chew

This paper demonstrates that dual targeting of TfR and CD98hc enhances brain exposure of large molecules compared to single-target approaches.

Cell Reports · Jul 22, 2025Peer-reviewedNeuroscience

Transferrin receptor-mediated transport at the blood-brain barrier is elevated in early development but maintained across adult aging

Vanessa O. Torres, Michelle E. Pizzo, Darren Chan, Jason C. Dugas, David Huynh, David A. Joy, Eric Liang, Lily Sarrafha, Isabel A. Becerra, Roni Chau, Kylie S. Chew, Johann Chow, Timothy Earr, Nathalie Khoury, Kendra J. Lechtenberg, , Y. Joy Yu Zuchero

This study investigates TfR-mediated BBB transport in mice across development and aging, finding elevated transport in early development and stability across adulthood, including in an AD model.

bioRxiv · Nov 12, 2024 · PreprintNeuroscience