Author

Lawrence A. Stern

City Of Hope National Medical CenterORCID 0000-0002-3369-7495Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Stephen J. FormaniD· 2 shared Anthony J. ParkiD· 1 shared Bea ParcutelaiD· 1 shared Brenda AguilariD· 1 shared Candi Trac· 1 shared Carl H. JuneiD· 1 shared Catalina Martinez· 1 shared Cheng-Fu KuoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Stephen J. FormanORCID

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Author profile →

2 papers

Recent·Most cited

Meditope-Enabled Chimeric Antigen Receptors Facilitate Plug-and-Play Control of T Cells

Cheng-Fu Kuo, Zhen Tong, Yi‐Chiu Kuo, Miso Park, Jeremy D. King, Kevin Ly, Bea Parcutela, Lawrence A. Stern, Zhiqiang Wang, Jonathan C. Hibbard, Brenda Aguilar, Renate Starr, Wen-Chung Chang, Julie R. Ostberg, Daniel J. Rossi, , Christine E. Brown

This study develops meditope-enabled CARs to improve T cell functionality and address tumor heterogeneity in CAR therapy.

Cancer Immunology Research · Aug 4, 2026Peer-reviewedBioengineering

Solid tumor CAR T cells engineered with fusion proteins targeting PDL1 for localized IL-12 delivery

John Paul Murad, Lea Christian, Reginaldo Cruz Alves Rosa, Yuwei Ren, Eric Lee, Lupita S. Lopez, Anthony J. Park, Jason Yang, Candi Trac, Lauren N. Adkins, Wen‐Chung Chang, Catalina Martinez, Carl H. June, Stephen J. Forman, Jun Ishihara, , Saul J. Priceman

This study engineers CAR T cells with PDL1-IL12 fusion proteins to enhance anti-tumor responses in solid tumors by improving T cell function and reducing systemic inflammation.

bioRxiv · Apr 4, 2025 · PreprintBioengineering