Zinc finger protein SALL4 functions through an AT-rich motif to regulate gene expression
Nikki R. Kong, Mahmoud Adel Bassal, Hong Kee Tan, Jesse V. Kurland, Kol Jia Yong, John J. Young, Yang Yang, Fudong Li, Jonathan D. Lee, Yue Liu, Chan-Shuo Wu, Alicia J. Stein, Hongbo Robert Luo, Leslie E. Silberstein, Martha L. Bulyk, , Li Chai
The paper identifies the DNA binding domain and sequence of SALL4, discovers its target genes in liver cancer cells, and reveals its mechanism of gene regulation.
Cell Reports · Jan 1, 2020Peer-reviewedMolecular Biology