Author

Seung Won Shin

QB3ORCID 0000-0002-3437-4161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Iain C. ClarkiD· 3 shared Kevin M. JosliniD· 2 shared Adam R. AbateiD· 1 shared Atsuki KawamuraiD· 1 shared Chenchen Xia· 1 shared Chunyu WangiD· 1 shared James Pai· 1 shared K. Christopher GarcíaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioengineering

Iain C. ClarkORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell DNA cytometry with magnetic- and fluorescence-activated bead sorting

Seung Won Shin, Sakshi Shah, Chenchen Xia, Atsuki Kawamura, Zhihui Wang, Yuanrong Kang, Nicole Klatt, Iain C. Clark

The paper introduces magniFIND-seq, a method for single-cell DNA and RNA analysis using digital PCR and commercial sorting instruments, enabling high-purity isolation of rare cell populations.

bioRxiv · Sep 18, 2026 · PreprintBioengineering

Functional Pairing of TCR-peptide-MHC Interactomes by Single-cell Clonal Expansion

Liu Daisy Liu, Seung Won Shin, Kevin M. Joslin, Chunyu Wang, James Pai, Rong Ma, Xinyu Xiang, Iain C. Clark, K. Christopher García

The paper develops LINC-seq to identify functional TCR-pMHC pairs by clonal expansion and deep mutational scanning, achieving high accuracy in recovering known cognate pairs and resolving co-evolutionary interactions.

bioRxiv · Aug 23, 2026 · PreprintImmunology

Deterministic Cell Pairing with Simultaneous Microfluidic Merging and Sorting of Droplets

Kevin M. Joslin, Sophia Dateshidze, Seung Won Shin, Adam R. Abate, Iain C. Clark

This paper introduces a microfluidic platform that deterministically pairs and sorts droplets containing cells, achieving high recovery of target cell pairs for studying cell crosstalk.

Lab on a Chip · Jan 1, 2025Peer-reviewedBioengineering