Bridget M. Barker

This study identifies novel diagnostic antigens for coccidioidomycosis using high-dimensional peptide serology, showing improved accuracy in distinguishing infected individuals from controls.

The paper analyzes genome variation in Sporothrix species to understand their evolutionary strategies and drug resistance mechanisms.

This study characterizes two clinical Sarocladium spinificis strains that inhibit Coccidioides posadasii growth, revealing their genomic features and potential antifungal properties.

The paper tests existing drugs for antifungal activity against Coccidioides in mice, finding that sertraline combined with fluconazole reduces lung fungal load.

The paper develops a method to infer strain composition in microbial mixed cultures using natural SNPs as barcodes, validated on Coccidioides posadasii isolates and applied to GWAS.

The paper identifies a defensin-like gene in Coccidioides posadasii with high transcript levels in spherules and uses CRISPR-Cas9 to delete it.

The paper presents a chromosomal-level genome assembly of the Coccidioides posadasii Silveira strain using SMRT sequencing, improving genome annotation and enabling future genomic studies.

The paper assembles and annotates mitochondrial genomes of Coccidioides immitis and C. posadasii, and assesses population variation across 77 genomes, identifying common genes and introns.