Kohei Arakawa

A Col22a1-EGFP reporter reveals dynamic three-dimensional organization of the myotendinous junction

This study uses a Col22a1-EGFP reporter to visualize and analyze the dynamic three-dimensional structure of the myotendinous junction across development and in response to mechanical stress.

Novel Biomaterial-Based Synovial Fluid Analysis Reveals Protective microRNA Signatures in a Mouse Model of Acute Synovitis-Driven Osteoarthritis

This study uses a mouse model to investigate how acute synovitis and mechanical stress contribute to PTOA, identifying miRNA signatures in synovial fluid that may protect against cartilage degeneration.

A Novel Slow-Progressive Knee Osteoarthritis Murine Model Induced by Non-Invasive Posterior Cruciate Ligament Rupture in Mice

This study develops a murine model of slow-progressing knee osteoarthritis by inducing non-invasive posterior cruciate ligament rupture and compares its progression to the destabilized medial meniscus model.

Concurrent Joint Contact in Anterior Cruciate Ligament Injury induces cartilage micro-injury and subchondral bone sclerosis, resulting in knee osteoarthritis

This study compares the effects of cartilage compression and joint instability on post-traumatic osteoarthritis progression after ACL injury in mice.

Effectiveness of Exercise Intervention in Preventing Active Arthritis Exacerbation in an SKG Mouse Model of Rheumatoid Arthritis

This study shows that low-intensity exercise reduces arthritis severity and inflammation in SKG mice with rheumatoid arthritis.

Joint Instability Causes Catabolic Enzyme Production in Chondrocytes prior to Synovial Cells in Novel Non-Invasive ACL ruptured Mouse Model

This study establishes a non-invasive ACL-ruptured mouse model to investigate OA progression, finding that chondrocytes respond to mechanical stress before synovial cells.